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Precision Medicine, the New Standard of Care

ActX makes it possible to bring the power of genomics into your practice, without disrupting your workflow.

Precision medicine is a significant leap towards improving the standard of care and replacing the one size fits all approach to medicine.

Making Precision Medicine Simple

  • Evidence based, actionable genomic decision support.
  • Real time alerts through your EHR for adverse drug reactions and serious hereditary risks.
  • Continuously updated decision support based on the latest literature with clinical recommendations.
  • Easy access to your patient's information (EHR, secure web access and mobile app).

Drug-genome Interactions

Integrated into your electronic health record, every time you write a prescription, ActX checks the drug against the patient's genetics, alerting you only if there's an issue with:
  • Adverse drug reactions
  • Efficacy
  • Dosing
ActX covers all common U.S. prescription drugs. For example, a significant percentage of the U.S. population likely gets no pain relief from codeine, based on their genetics, and ActX can alert you to these patients.

Actionable Genetic Risks

In your electronic health record, the ActX patient genomic profile shows actionable patient genomic risks. For example, patients with Lynch Syndrome, a genetic condition, can have up to a 70% lifetime risk of colorectal cancer, which can be detected at an early stage through colonoscopy starting at a young age.

Carrier Status Coverage

ActX’s carrier status panel now includes over 180 conditions that can help inform you and your patients about the risk of parents passing on serious recessive genetic conditions to their children. Carriers normally do not have the disease. Instead, carriers are patients who have a genetic variant that can be passed down to their offspring. Usually, the disease is recessive, meaning carriers who only have a single variant do not display symptoms of the disease. When two carriers have children together, there generally is a one in four chance that the child could inherit both disease-causing variants from their parents and develop the disease.

How does it Work?

In addition to our real-time Genomic Decision Support℠ Service, ActX makes it easy to obtain your patient's genetics using a small amount of saliva.

After you authorize it, your patient:
  1. Receives an email allowing them to sign up for the ActX service.
  2. Signs up on the ActX website and pays for the service (the service is currently paid for by patients and not yet covered by insurance)
  3. Receives a saliva collection kit at their home
  4. Spits 1 cc into a tube and then mails it directly to our CLIA certified laboratory, where it will be genotyped or sequenced.
After quality assurance, the ActX Genomic Decision Support℠ Service will be activated. You will be alerted when your patient's data is available, and when any immediate or subsequent serious medical risks are found. If you are using a partner EHR, then every time you write a prescription, it will be checked for drug-genomic interactions, and you can access an up-to-date patient Genomic Profile in the EHR at any time.

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